Benefits to Customers

Comparative Odds-Ratios for the Predefined Adverse Events

Adverse Event	Dataset	Odds Ratio	95% Confidence Interval
Adverse Event	Dataset	Odds Ratio	*Upper*	*Lower*
Dehydration	DATA1	1.062	1.254	0.900
Dehydration	DATA2	1.865	2.258	1.540
Gastric Pain	DATA1	1.516	1.992	1.154
Gastric Pain	DATA2	2.821	3.898	2.041
Fecal Impaction	DATA1	3.187	4.108	2.473
Fecal Impaction	DATA2	4.098	5.481	3.064
Post-Operative Ileus	DATA1	2.068	2.291	1.867
Post-Operative Ileus	DATA2	1.731	2.291	1.308
Other Bowel Obstruction	DATA1	1.167	1.610	0.845
Other Bowel Obstruction	DATA2	1.698	2.333	1.236
Constipation	DATA1	3.120	3.344	2.911
Constipation	DATA2	6.056	6.582	5.572
Nausea with Vomiting	DATA1	3.322	3.588	3.076
Nausea with Vomiting	DATA2	9.224	10.241	8.308
Nausea Only	DATA1[1]	3.864	4.193	3.560
Nausea Only	DATA2[2]	25.300	28.020	22.843
Vomiting Only	DATA1	3.547	4.591	2.741
Vomiting Only	DATA2	4.985	6.723	3.697
Abdominal Pain	DATA1	1.977	2.294	1.704
Abdominal Pain	DATA2	2.007	2.284	1.764
Poisoning-Opiates	DATA1	4.165	8.795	1.973
Poisoning-Opiates	DATA2	1.223	3.811	0.392
Pruritus	DATA1[3]	6.653	7.320	6.046
Pruritus	DATA2[4]	64.144	71.709	57.378

[1] The odds ratio for anesthesia for “Nausea Only” in DATA1 was 10.185.

[2] The odds ratio for anesthesia for “Nausea Only” in DATA2 was 7.320.

[3] The odds ratio for anesthesia for Pruritus in DATA1 was 25.061.

[4] The odds ratio for anesthesia for Pruritus in DATA2 was 7.386.

Transformed Semi-logarithmic estimates for total cost for DATA1 and DATA2: Percent change and absolute change from the intercept

Total Cost
	DATA1		DATA2
Adverse Event	Percent Change in Cost †¹⁴	Change in Cost at the Intercept	Percent Change in Cost †	Change in Cost at the Intercept
Adverse Event	Percent Change in Cost †¹⁴	Change in Cost at the Intercept	Percent Change in Cost †	Change in Cost at the Intercept
Dehydration	-14.52%	-$656.25	14.64%	$752.79
Gastric Pain	-2.04%	-$92.10	-0.32%	-$16.53
Fecal Impaction	-2.99%	-$135.01	19.08%	$981.55
Post-Operative Ileus	85.96%	$3,883.79	93.05%	$4,785.96
Other Bowel Obstruction	7.03%	$317.85	31.92%	$1,641.56
Constipation	7.40%	$334.14	18.26%	$939.20
Vomit Post-GI Surgery	23.47%	$1,060.56	4.14%	$212.74
Nausea With Vomiting	1.72%	$77.65	1.88%	$96.46
Nausea Only	20.28%	$916.49	11.94%	$614.29
Vomiting Only	-7.11%	-$321.31	-1.97%	-$101.33
Abdominal Pain	-11.52%	-$520.41	-3.36%	-$172.95
Poisoning-Opiates	4.31%	$194.81	15.39%	$791.44
Pruritus	17.83%	$805.77	22.43%	$1,153.53
† The formula used for conversion is: exp(β-[VAR/2])-1 where β is the parameter estimate and VAR is the variance of the parameter estimate. For an explanation of this formula, see P. Kennedy, "Variables in Semilogarithmic Equations," Amer. Econ. Rev., 1981, 71, 801-802.

ADVERSE EVENTS IN DATA1

Fecal Impaction

Post-Operative Ileus

Other Bowel Obstruction

Nausea with Vomiting

Poisoning-Opiates

TOTAL COST IN DATA1

Log of Total Cost

LENGTH OF STAY IN DATA1

Log of Length of Stay

ADVERSE EVENTS IN DATA2

Fecal Impaction

Post-Operative Ileus

Other Bowel Obstruction

Nausea with Vomiting

Poisoning-Opiates

TOTAL COST IN DATA2

Log of Total Cost

TOTAL LENGTH OF STAY IN DATA2

Log of Length of Stay